Volume 27, No 4 (2014)

Editorial (by invitation only)

Helicobacter pylori infection and gastroesophageal cancer: unveiling a Hamletic dilemma

Angelo Zullo, Cesare Hassan, Vincenzo De Francesco, Raffaele Manta, Adriana Romiti, Luigi Gatta

291
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Invited Reviews

The history of genetics in inflammatory bowel disease

Weronica E. Ek, Mauro D'Amato, Jonas Halfvarson

294
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Therapeutic drug monitoring in inflammatory bowel disease

Uri Kopylov, Shomron Ben-Horin, Ernest Seidman

304
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Optimizing post-operative Crohn's disease treatment

Eugeni DomÃ¨nech, MÃriam MaÃ±osa, Triana LobatÃ³n, Eduard CabrÃ©

313
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Recent developments in the surgical management of perianal fistula for Crohn's disease

Cristina B. Geltzeiler, Nicole Wieghard, Vassiliki L. Tsikitis

320
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Sofosbuvir: a novel oral agent for chronic hepatitis C

Evangelos Cholongitas, George V. Papatheodoridis

331
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Review

Study design considerations for irritable bowel syndrome clinical trials

Larry E. Miller

338
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Original Articles

Anti-reflux mucosectomy for gastroesophageal reflux disease in the absence of hiatus hernia: a pilot study

Haruhiro Inoue, Hiroaki Ito, Haruo Ikeda, Chiaki Sato, Hiroki Sato, Chainarong Phalanusitthepha, Bu'Hussain Hayee, Nikolas Eleftheriadis, Shin-ei Kudo

346
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Patients with established gastro-esophageal reflux disease might benefit from Helicobacter pylori eradication

John M. Moschos, George Kouklakis, Stergios Vradelis, Petros Zezos, Michael Pitiakoudis, Dimitrios Chatzopoulos, Christos Zavos, Jannis Kountouras

352
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First- and second-line Helicobacter pylori eradication with modified sequential therapy and modified levofl oxacin-amoxicillin-based triple therapy

Angelo Zullo, Lorenzo Ridola, Cesare Efrati, Floriana Giorgio, Giorgia Nicolini, Claudio Cannaviello, Domenico Alvaro, Cesare Hassan, Luigi Gatta, Vincenzo De Francesco

357
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Normal values and reproducibility of the real-time index of vagal tone in healthy humans: a multi-center study

Adam Donald Farmer, Steven J. Coen, Michiko Kano, Nathalie Weltens, Huynh Giao Ly, Claude Botha, Peter A. Paine, Lukas Van Oudenhove, Qasim Aziz

362
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Effectiveness of adalimumab for ambulatory ulcerative colitis patients after failure of infliximab treatment: a first "real-life" experience in primary gastroenterology centers in Italy

Antonio Tursi, Walter Elisei, Marcello Picchio, Antonio Penna, Giacomo Forti, Gian Marco Giorgetti, Roberto Faggiani, Costantino Zampaletta, Giorgio Pelecca, Giovanni Brandimarte

369
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Risk factors of cellulitis in cirrhosis and antibiotic prophylaxis in preventing recurrence

Rooby Hamza Erachamveettil, Mashhood Padincharepurathu Villyoth, George Peter, Deni Joseph, Chethan Govindaraju, Devang Chandrakanth Tank, Sreejaya Sreesh, Premalatha Narayanan, Kattoor Ramakrishnan Vinayakumar

374
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Virologic response and breakthrough in chronic hepatitis B Egyptian patients receiving lamivudine therapy

Sohair Ismail, Hanan Abdel Hafez, Samar K. Darweesh, Kamal Hassan Kamal, Gamal Esmat

380
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The hepatoprotective and hypolipidemic effects of Spirulina (Arthrospira platensis) supplementation in a Cretan population with non-alcoholic fatty liver disease: a prospective pilot study

Elias E. Mazokopakis, Maria G. Papadomanolaki, Andreas A. Fousteris, Dimitrios A. Kotsiris, Ioannis M. Lampadakis, Emmanuel S. Ganotakis

387
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Vascular invasion does not discriminate between pancreatic tuberculosis and pancreatic malignancy: a case series

Surinder S. Rana, Vishal Sharma, Sathosh Sampath, Ravi Sharma, Bhagwant R. Mittal, Deepak K. Bhasin

395
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Isolated microorganisms in plastic biliary stents placed for benign and malignant diseases

Paris Basioukas, Antonios Vezakis, Olympia Zarkotou, Georgios Fragulidis, Katerina Themeli-Digalaki, Spyros Rizos, Andreas Polydorou

399
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Can early endoscopic ultrasound predict pancreatic necrosis in acute pancreatitis?

Surinder S. Rana, Deepak K. Bhasin, Vishal Sharma, Ravi Sharma, Vinita Chaudhary, Puneet Chhabra

404
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Images of the Month

Malignant mesothelioma presenting as dysphagia diagnosed by endoscopic ultrasound

Badr Al-Bawardy, Emmanuel C. Gorospe, Cadman Leggett

409
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Unusual presentation of a gastrointestinal stromal tumor of the duodenum mimicking an inflammatory enlargement of a peripancreatic lymph node

Gianfranco Donatelli, Bertrand M. Vergeau, Gilles Roseau, Bruno Meduri

410
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Inverted colonic diverticulum

Tarik Adioui, Hassan Seddik

411
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Cutting a diagnostic Gordian knot by endoscopic mucosal resection: mantle cell lymphoma relapse in a patient with left-sided colonic polyps

Georgios Kechagias, Georgios Tribonias, Georgios Andreou, Dimitrios G. Karamanolis

412
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Case Reports

Enteral stenting for gastric outlet obstruction and afferent limb syndrome following pancreaticoduodenectomy

Wilson T. Kwong, Syed M. Fehmi, Andrew M. Lowy, Thomas J. Savides

413
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Telogen effluvium as the first symptom of Crohn's disease in a child

Maria Rogalidou, Meropi Tzoufi, Konstantinos Katsanos, Georgios Gaitanis, Aikaterini Zioga, Epameinondas Tsianos, Antigoni Siamopoulou-Mavridou

418
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Novel use of endoscopically placed fiducial markers for targeted radiation therapy of colonic lymphomas

Grigoriy E. Gurvits, Joseph Marsano, Boris Kobrinsky, Samuel Shin, Nicholas Sanfilippo, Dmitri Volkov

421
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Clinical Opinions

Are we on our way to change our mode of thinking and treating inflammatory bowel disease patients?

Fernando Magro, Rami Eliakim

424
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EPISOD puts an end to sphincter of Oddi dysfunction type III

Jeffrey D. Mosko, Ram Chuttani

427
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Letter to the Editor

The role of protease-activated receptors in regulating other ion channels

Michael Eisenhut

429
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Is the use of non-selective beta-blockers necessary in cirrhotic patients with small varices?

Xingshun Qi, Xiaozhong Guo, Daiming Fan

429
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Successful peroral endoscopic myotomy for radical treatment of sigmoid-type esophageal achalasia by Greek gastroenterologists

Nikolas Eleftheriadis, Andreas Protopapas, John Katsogridakis, Apostolos I. Hatzitolios

430
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Neutrophil-to-lymphocyte ratio as a sensitive marker in diagnosis of celiac disease

Murat Sarikaya, Zeynal Dogan, Bilal Ergul, Levent Filik

431
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Primary aldosteronism during long-term ulcerative colitis: a diagnostic challenge

John K. Triantafillidis, George Malgarinos, Achilleas Rentis, Konstantinos Vagianos

432
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Development of Crohn's disease in husband and wife: the role of major psychological stress

John K. Triantafillidis, Charalambos Spyropoulos, Achilleas Rentis, Konstantinos Vagianos

433
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Large fundal varices: to glue or not to glue?

Syed Adnan Mohiuddin, Manik Sharma, Ragesh Babu Thandassery, Muneera Al Mohannadi, Rafie Yacoob, Ahmed Muzrakchi, Saad Rashid Al Kaabi

434
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Tuberculous peritonitis after treatment for chronic hepatitis C

Evangelos Cholongitas, Theodora Nakouti, Evangelos Akriviadis

435
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Right-sided pancreaticopleural fistula

Larisa Vasilieva, Sofia Adamidi, Naso Kittou, Konstantinos Papiris, Andreas Romanos, Spyros P. Dourakis

436
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Extensive cervical, thoracic, and abdominal wall emphysema and pneumomediastinum following ERCP: a rare scenario

Anil K John, Ragesh Babu Thandassery, Syed Hammad Alam, Saad Rashid Al Kaabi

437
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Table of contents

Editorial (by invitation only)

Invited Reviews

Review

Original Articles

Images of the Month

Case Reports

Clinical Opinions

Letter to the Editor