Improved optical identification of laterally spreading type "0-IIb" gastric lesion with narrow band imaging magnification endoscopy

Nikolas Eleftheriadis; Haruhiro Inoue; Haruo Ikeda; Roberta Maselli; Manabu Onimaru; Akira Yoshida; Hiroaki Ito; Shigeharu Hamatani; Shin-ei Kudo

Authors Nikolas Eleftheriadis, Haruhiro Inoue, Haruo Ikeda, Roberta Maselli, Manabu Onimaru, Akira Yoshida, Hiroaki Ito, Shigeharu Hamatani, Shin-ei Kudo.

Abstract

Endoscopic submucosal dissection (ESD) has become the treatment of choice for early gastric cancer. Accurate identification of tumor borders is crucial for curative ESD. Narrow band imaging magnification endoscopy (NBI-ME) has been effectively used for assessment of superficial gastric lesions; however, international experience in type "0-IIb" gastric lesions is limited. Successful endoscopic tissue characterization of laterally spreading type "0-IIb" early gastric cancer in a 74-year-old male with known type "0-IIa" lesion, using zoom NBI-ME, is reported. While the type "0-IIa" gastric lesion was clearly recognized by white light endoscopy and indigo carmine chromoendoscopy, the laterally spreading type "0-IIb" gastric cancer was only identified on the basis of NBI-ME malignant microvascular and mucosal microsurface pattern. Based on NBI-ME findings, accurate border marking approximately 1 mm apart from the demarcation line and complete en bloc ESD resection of both tumors was successfully succeeded. Recovery was uneventful. Histopathology showed moderately differentiated gastric adenocarcinoma in type "0-IIa" lesion and a small area of low-grade well-differentiated gastric adenocarcinoma in type "0-IIb" lesion. Conclusively, improved real-time optical identification of laterally spreading type "0-IIb" gastric lesion was achieved with NBI-ME.

Keywords Narrow band imaging, magnifying endoscopy, early gastric cancer, endoscopic submucosal dissection

Ann Gastroenterol 2014; 27 (3): 267-269