Marek Ruszczyński, Magdalena Urbańska, Hania Szajewska
The Medical University of Warsaw, Poland
Department of Paediatrics, The Medical University of Warsaw, Poland
We appreciate Dr. Rupérez’s comment that the potential mechanism of action of gelatin tannate is linked exclusively to its undissociated form. We feel it is an important addition to our manuscript. However, to judge this mechanism in more detail, we are looking forward to reading a full publication by Bueno et al.
Regardless of the mechanism of action of gelatin tannate, our conclusions remain valid. Currently, there is no evidence to support the use of gelatin tannate for treating acute gastroenteritis in children and only sparse evidence to support the use of gelatin tannate in adults.